Dr Ann Hunter

Qualifications

BSc (Hons) Chemistry and Analytical Science (University of Wales, Swansea, 1990)

PhD in Chromatographic, Capillary Electrophoretic and Mass Spectrometric Studies of Proteins and Smaller Biomolecules (Mass Spectrometry Research Unit, Univeristy of Wales, Swansea 1994)

Teaching

PMC-101 Organic Chemistry: An Introduction for Life Sciences

PMC-102 Chemical Analysis: from Composition to Structure Elucidation; an Introduction for Life Sciences

PM-273 Advances in Toxicology: Pick your Poison

PM-355 Drug Development and Regulation

PMLM01 Analytical Techniques for Medicinal Chemistry and Nanomedicine

Publications

2016

Patel C, Bassin JP, Scott M, Flye J, Hunter AP, Martin L, Goyal M, Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives. Molecules. 2016, 21 (7).

2009

Brenton AG, Godfrey AR, Alamri M, Stein BK, Williams CM, Hunter AP, Wyatt MF, Analysis of large historical accurate mass data sets on sector mass spectrometers. Rapid Communications in Mass Spectrometry. 2009, 23 (21), 3484-3487.

2007

Hunter AP, Lees AMJ, Platt AWG, Synthesis, structures and mass spectrometry of lanthanide nitrate complexes with tricyclohexylphosphine oxide. Polyhedron. 2007, 26 (17), 4865-4876.

2003

Davies RJH, Stevenson C, Kumar S, Lyle J, Cosby L, Malone JF, Boyd DR, Sharma ND, Hunter AP, Stein BK, Oxidation of guanine Nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane. Nucleosides Nucleotides & Nucleic Acids. 2003, 22 (5-8), 1355-1357.

2002

Davies RJH, Stevenson C, Kumar S, Lyle J, Cosby L, Malone JF, Boyd DR, Sharma ND, Hunter AP, Stein BK, Novel oxidation products from guanine nucleosides reacted with dimethyldioxirane. Chemical Communications. 2002, (13), 1378-1379.

2001

Zamze S, Wing DR, Wormald MR, Hunter AP, Dwek RA, Harvey DJ, A family of novel, acidic N-glycans in Bowes melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core. European Journal of Biochemistry. 2001, 268 (14), 4063-4078.

1999

Wedgwood JL, Hunter AP, Kresinski RA, Platt AWG, Stein BK, Water soluble platinum(II) and palladium(II) complexes of alkyl sulfonated phosphines. Inorganica Chimica Acta. 1999, 290 (2), 189-196.

Newton JP, Hunter AP, Simmons DL, Buckley CD, Harvey DJ, CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated. Biochemical and Biophysical Research Communications. 1999, 261 (2), 283-291.

Koenigs LL, Peter RM, Hunter AP, Haining RL, Rettie AE, Friedberg T, Pritchard MP, Shou M, Rushmore TH, Trager WF, Electrospray ionization mass spectrometric analysis of intact cytochrome P450: Identification of tienilic acid adducts to P450 2C9. Biochemistry. 1999, 38 (8), 2312-2319.

Harvey DJ, Hunter AP, Bateman RH, Brown J, Critchley G, Relationship between in-source and post-source fragment ions in the matrix-assisted laser desorption (ionization) mass spectra of carbohydrates recorded with reflectron time-of-flight mass spectrometers. International Journal of Mass Spectrometry. 1999, 188 (1-2), 131-146 .

1998

Kuster B, Hunter AP, Wheeler SF, Dwek RA, Harvey DJ, Structural determination of N-linked carbohydrates by matrix-assisted laser desorption/ionization mass spectrometry following enzymatic release within sodium dodecyl sulphate polyacrylamide electrophoresis gels: Application to species-specific glycosylation of alpha(1)-acid glycoprotein. Electrophoresis. 1998, 19 (11), 1950-1959.

Harvey DJ, Hunter AP, Use of a conventional point detector to record matrix-assisted laser desorption/ionization spectra from a magnetic sector instrument. Rapid Communications in Mass Spectrometry. 1998, 12 (22), 1721-1726.

Guile GR, Harvey DJ, O'Donnell N, Powell AK, Hunter AP, Zamze S, Fernandes DL, Dwek RA, Wing DR, Identification of highly fucosylated N-linked oligosaccharides from the human parotid gland. European Journal of Biochemistry. 1998, 258 (2), 623-656.

1997

Marshall AD, Darbyshire JF, Hunter AP, McPhie P, Jakoby WB, Control of activity through oxidative modification at the conserved residue Cys(66) of aryl sulfotransferase IV. Journal of Biological Chemistry. 1997, 272 (14), 9153-9160.

Kuster B, Wheeler SF, Hunter AP, Dwek RA, Harvey DJ, Sequencing of N-linked oligosaccharides directly from protein gels: In-gel deglycosylation followed by matrix-assisted laser desorption/ionization mass spectrometry and normal-phase high-performance liquid chromatography. Analytical Biochemistry. 1997, 250 (1), 82-101.

Haining RL, Hunter AP, Sadeque AJM, Philpot RM, Rettie AE, Baculovirus-mediated expression and purification of human FMO3 - Catalytic, immunochemical, and structural characterization. Drug Metabolism and Disposition. 1997, 25 (7), 790-797.

Amore BM, Kalhorn TF, Skiles GL, Hunter AP, Bennett GD, Finnell RH, Nelson SD, Slattery JT, Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity. Drug Metabolism and Disposition. 1997, 25 (8), 953-962.

1996

Haining RL, Hunter AP, Veronese ME, Trager WF, Rettie AE, Allelic variants of human cytochrome P450 2C9: Baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms. Archives of Biochemistry and Biophysics. 1996, 333 (2), 447-458.

1995

Hunter AP, Games DE, Evaluation of glycosylation site heterogeneity of glycopeptides in proteolytic digests of bovine alpha(a)-acid glycoprotein by mass spectrometry. Rapid Communications in Mass Spectrometry. 1995, 9 (1), 42-56.

1994

Hunter AP, Severs JC, Harris FM, Games DE, Proton transfer reactions of mass-selected muliply-charged ions. Rapid Communications in Mass Spectrometry. 1994, 8 (5), 417-422.

Hunter AP, Games DE, Chromatographic and mass spectrometric methods for the identification of phosphorylation sites in phosphoproteins. Rapid Communications in Mass Spectrometry. 1994, 8 (7), 559-570.

Educational Resources

Waters Corp, Owen RN, Hunter AP, Wyatt MF. ACQUITY QDa Practical MS Education Package. Item no. 715005631 Waters Corp (2018).

Affiliations

British Mass Spectrometry Society