Yeast has been used as a tool in a number of Nobel Prize winning discoveries in Physiology/Medicine since 2001. An overview of these achievements can be found here.
The Cytochrome P450 Homepage is an extensive repository of cytochromes P450 from all kingdoms of life. It is manually curated by David Nelson and the nomenclature system used conforms to the internationally agreed rule that members of the cytochrome P450 families and subfamilies share common ancestors.
The Fungal Cytochrome P450 Database is a repository of cytochromes P450 found in fungi.
Allele nomenclature for human cytochrome P450 enzymes.
Review of microbial cytochrome P450 enzymes.
Review of cytochrome P450 enzymes with novel properties.
LIFE is dedicated to improving the health of those people suffering from fungal disease (allergy and infection) by increasing awareness, improved diagnosis, and improving access to fungal therapies, worldwide. The initiative is led by Professor David Denning.
This natural products discovery and bioengineering network is funded by BBSRC and aims to bring together chemists, biologists, computational scientists and engineers from academia and industry to accelerate the natural products discovery and bioengineering process.
STEROLTALK is a Specific Targeted Research Project within the thematic priority of Life Sciences, genomics and biotechnology for health of the 6th Framework Programme of the European Commission. The STEROLTALK project unites 10 academic and industrial institutions from 7 countries for a period of three years starting September 2005. The consortium aims to develop a global approach for the discovery of neew drug targets, new chemical entities and therapeutic strategies for treatment of cardiovascular disease and establishment of drug-drug interactions.
This network will utilize genomics-based integrated approaches to study antifungal resistance in relevant fungal pathogens (Candida, Aspergillus). This network will study distinct resistance mechanisms target mutations, drug efflux, signal transduction, transcriptional activation, cell wall alterations, biofilm formation) all of which can contribute individually or in combination to antifungal resistance in clinical isolates.
The Athena SWAN Charter recognises excellence in Science, Technology, Engineering, Medicine and Mathematics (STEMM) employment in Higher Education. Prof. Diane Kelly is the Chair of the Swansea University Medical School Self-Assessment team at Swansea University.