Dr Claire Price
FHEA MRSB MRSC
Senior Lecturer in Biomedical Science
Qualifications
BSc (hons) Physiology (Cardiff University, 2006)
PhD (Swansea University, 2012)
Teaching
PM-004 Fundamentals of Microbiology and Disease
PM-008 Foundational Skills Development 2
PM-134 Microbiology
PM-250 Infectious Disease
PM-256 Communicating Medical Sciences
PM-280 Skills for Researchers
PM-340 Being a Medical Scientist
PM-344 Capstone Project
PM-354 Cancer Pharmacology
PM-366 Teaching Science in Schools
PMBM01 Research & Innovation in Biomedical Science
PMBM02 Introduction to Biomedical Science Practice in Health Care
PMRM00 Introduction to the Practice of Medical Physicists & Clinical Engineers in Health Care
PMBM03 Fundamentals of Biomedical Science
PMBM03J Fundamentals of Biomedical Science
PMCB01 Clinical Biochemistry for Biomedical Scientists
PMRM04 Dissertation Research
PMRM04J Dissertation Research
Publications
2023
Weston D, Price CL. A Systematic Review on the Impacts of Virtual Learners Communication and Social Skill Development Following the Return of Face-To-Face Education. EdArXiv, 2023. https://edarxiv.org/rkjqn/
2022
Price CL, Warrilow AGS, Rolley NJ, Parker JE, Thoss V, Kelly D, Corcionivoschi N, Kelly SL. Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids. PLOS ONE, 2022. https://doi.org/10.1371/journal.pone.0265227.
2019
Warrilow AGS, Parker JE, Price CL, Rolley NJ, Nes WD, Kelly DE, Kelly SL. Isavuconazole and voriconazole inhibition of sterol 14α-demethylases (CYP51) from Aspergillus fumigatus and Homo sapiens. International Journal of Antimicrobial Agents. 2019, EPub before print.
Lamb DC, Follmer AH, Goldstone JV, Nelson DR, Warrilow AG, Price CL, True MY, Kelly SL, Poulos TL, Stegeman JJ. On the occurrence of cytochrome P450 in viruses. 2019. DOI: 10.1073/pnas.1901080116.
Warrilow AG, Nishimoto AT, Parker JE, Price CL, Flowers SA, Kelly DE, Rogers PD, Kelly SL. The evolution of azole resistance in Candida albicans sterol 14α-demethylase (CYP51) through incremental amino acid substitutions. Antimicrobial Agents and Chemotherapy. 2019, EPub before print.
2018
Zhou W, Warrilow AGS, Thomas CD, Ramos E, Parker JE, Price CL, Vanderloop BH, Fisher PM, Loftis MD, Kelly DE, Kelly SL, Nes WD. Functional importance for developmental regulation of sterol biosynthesis in Acanthamoeba castellanii. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2018. In Press.
2017
Hull CM, Warrilow AGS, Rolley NJ, Price CL, Donnison IS, Kelly DE, Kelly SL. Co-production of 11alpha-hydroxyprogesterone and ethanol using recombinant yeast expressing fungal steroid hydroxylases. Biotechnol Biofuels. 2017, 10:226.
Warrilow AGS, Parker JE, Price CL, Garvey EP, Hoekstra WJ, Schotzinger RJ, Wiederhold NP, Nes WD, Kelly DE, Kelly SL. The tetrazole VT-1161 is a potent inhibitor of Trichophyton rubrum through its inhibition of T. rubrum CYP51. Antimicrobial Agents and Chemotherapy. 2017, EPub ahead of print.
2016
Warrilow AG, Price CL, Parker JE, Rolley NJ, Smyrniotis CJ, Hughes DD, Thoss V, Nes WD, Kelly DE, Holman TR, Kelly SL. Azole antifungal sensitivity of sterol 14α-demethylase (CYP51) and CYP5218 from Malassezia globosa. Scientific Reports. 2016, 6, 27690.
Warrilow AG, Parker JE, Price CL, Nes WD, Garvey EP, Hoekstra WJ, Schotzinger RJ, Kelly DE, Kelly SL. The investigational drug VT-1129 is a highly potent inhibitor of Cryptococcus species CYP51 but only weakly inhibits the human enzyme. Antimicrobial Agents and Chemotherapy. 2016, 60(8), 4530-4538.
2015
Warrilow AGS, Parker JE, Price CL, Nes WD, Kelly SL, Kelly DE. CYP51-mediated azole resistance in Aspergillus fumigatus: an in vitro biochemical study. Antimicrobial Agents and Chemotherapy. 2015, 59(12), 7771-7778.
Price CL, Parker JE, Warrilow AGS, Kelly DE, Kelly SL. Azole fungicides - understanding resistance mechanisms in agricultural fungal pathogens. Pest Management Science. 2015, 71(8), 1054-1058.
Price CL, Warrilow AGS, Parker JE, Mullins JGL, Nes WD, Kelly DE, Kelly SL. Novel substrate specificity and temperature sensitive activity of Mycosphaerella graminicola CYP51 (MgCYP51) supported by the native NADPH cytochrome P450 reductase (CPR). Applied and Environmental Microbiology. 2015, 81(10), 3379-3386.
2014
Parker JE, Warrilow AGS, Price CL, Mullins JGL, Kelly DE, Kelly SL. Resistance to antifungals that target CYP51. Journal of Chemical Biology. 2014, 7(4), 143-161.
Affiliations
Member of the Royal Society of Biology
Member of the Biochemical Society
Member of the Royal Society of Chemistry
Fellow of the Higher Education Academy
STEM Ambassador