Dr Anna Seager
Areas of Expertise
- DNA damage
- Cell biology
- Image analysis
PM315 Genetic Analysis III
PM317 Genetics of Cancer
PMRM00 Introduction to the practice of Medical Physicists & Engineers in Health Care
Wilde EC, Chapman KE, Stannard LM, Seager AL, Brusehafer K, Ume-Kulsoom S, Tonkin JA, Brown MR, Verma JR, Doherty AT, Johnson GE, Doak SH, Jenkins GJS. A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. Archives of Toxicology. 2018, 92, 935-951.
Shah UK, Seager AL, Fowler P, Doak SH, Johnson GE, Scott SJ, Scott AD, Jenkins GJS. A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity. Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 2016, 808, 8-19.
Patni S, Bryant AH, Wynen LP, Seager AL, Morgan G, Thornton CA. Functional activity but not gene expression of toll-like receptors is decreased in the preterm versus term human placenta. Placenta. 2015, 36(9), 1031-1038.
Seager AL, Shah UK, Brüsehafer K, Wills J, Manshian B, Chapman KE, Thomas AD, Scott AD, Doherty AT, Doak SH, Johnson GE, Jenkins GJ. Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells. Mutagenesis. 2014, 29(3), 155-164.
Seager AL, Shah UK, Mikhail JM, Nelson BC, Marquis BJ, Doak SH, Johnson GE, Griffiths SM, Carmichael PL, Scott SJ, Scott AD, Jenkins GJ. Pro-oxidant induced DNA damage in human lymphoblastoid cells: homeostatic mechanisms of genotoxic tolerance. Toxicological Sciences. 2012, 128(2), 387-397.
Macfarlane TV, Seager AL, Moller M, Morgan G, Thornton CA. Thymic stromal lymphopoietin is present in human breast milk. Pediatric Allergy and Immunology. 2010, 21(2p2), e454.
Patni S, Wynen LP, Seager AL, Morgan G, White JO, Thornton CA. Expression and activity of Toll-like receptors 1-9 in the human term placenta and changes associated with labor at term. Biology of Reproduction. 2009, 80(2), 243-248.
Fellow of the Higher Education Academy